It happens more than twice a day, on average. Fists and feet were responsible for 745 murders in 2010, or 5.7 percent of all murders that year, according to FBI statistics. (The data on this have been remarkably stable in recent years. In the five preceding years, the percentage of murders perpetrated by fists or feet fluctuated between 5.6 and 6.1.)
Anecdotal evidence and boxing mechanics are discussed as well, but what is not mentioned is that a stat I vaguely recall that hands and feet cause more deaths than the dreaded evil "Assault Weapons".
"Assault Weapons" i.e. semi-auto rifles would only be a subset of All Rifles in the FBI Uniform Crime Report. In 2010 Rifles where used in 358 murders less than half the number for hands & feet. That trend continues back through the years.
It is a nice little stat to have in your toolbox and pull out next time you hear calls to renew the "Assault Weapons Ban".